From the mind of visionary filmmaker Zach Cregger (Weapons, Barbarian) comes a thrilling — and terrifying — reinvention of the Resident Evil franchise. In an all-new story, Resident Evil follows Bryan (Austin Abrams), a medical courier who unwittingly finds himself in an action-packed, non-stop race for survival as one fateful, horrifying night collapses around him in chaos.

Set in a post-apocalyptic world in which a virus has wiped out most of humanity, with survivors being terrorized by roaming scavengers called "Reapers." The protagonist is Hig, a pilot who survived the flu that killed everyone he knew, his wife included. He lives in the hangar of a small abandoned airport with his dog, his only neighbor a gun-toting ex-Marine. Hig sometimes heads off in his 1956 Cessna, where he can fish and pretend things are how they used to be. When a random transmission somehow beams through his radio, the voice ignites a hope deep inside him that a better life might exist if he flies a bit further. He risks it all. to chase a possible haven in Grand Junction.